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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
11.52
Human Site:
Y586
Identified Species:
16.89
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
Y586
S
I
D
S
T
S
S
Y
F
N
H
Y
R
S
H
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
F646
G
I
G
K
P
R
K
F
S
K
F
S
L
Y
K
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
C586
S
I
E
S
T
S
S
C
F
N
H
Y
R
S
H
Dog
Lupus familis
XP_545291
1075
123911
Y587
S
I
G
S
A
S
S
Y
C
N
H
C
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
Y586
S
I
D
S
T
S
S
Y
F
S
H
C
R
S
H
Rat
Rattus norvegicus
P70496
1074
123795
Y586
S
V
D
S
A
S
S
Y
F
N
H
Y
R
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
C585
S
I
D
S
E
S
S
C
C
N
P
F
R
S
Q
Frog
Xenopus laevis
NP_001129642
1039
119219
A561
L
G
K
S
K
K
F
A
K
F
S
L
Y
K
Q
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
R543
L
K
G
I
G
R
T
R
K
T
R
F
S
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
N832
A
L
E
G
M
K
L
N
T
P
E
M
E
R
K
Honey Bee
Apis mellifera
XP_001121004
1135
129725
M614
P
L
E
K
S
D
T
M
K
C
D
T
P
N
T
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
A895
S
G
M
D
F
A
S
A
A
E
K
Y
K
E
Y
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
F376
K
D
Y
Y
N
P
I
F
K
D
V
V
Q
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
C554
M
P
W
H
D
V
H
C
A
L
W
G
P
P
C
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
L771
L
W
T
K
H
S
M
L
N
L
H
P
N
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
6.6
86.6
66.6
N.A.
86.6
86.6
N.A.
0
60
6.6
0
N.A.
0
0
20
0
P-Site Similarity:
100
13.3
93.3
66.6
N.A.
93.3
93.3
N.A.
0
66.6
6.6
20
N.A.
20
33.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
13
7
0
13
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
19
13
7
0
13
0
0
7
% C
% Asp:
0
7
25
7
7
7
0
0
0
7
7
0
0
0
0
% D
% Glu:
0
0
19
0
7
0
0
0
0
7
7
0
7
7
7
% E
% Phe:
0
0
0
0
7
0
7
13
25
7
7
13
0
0
0
% F
% Gly:
7
13
19
7
7
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
7
7
0
7
0
0
0
38
0
0
0
32
% H
% Ile:
0
38
0
7
0
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
7
7
7
19
7
13
7
0
25
7
7
0
7
7
13
% K
% Leu:
19
13
0
0
0
0
7
7
0
13
0
7
7
7
0
% L
% Met:
7
0
7
0
7
0
7
7
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
7
7
32
0
0
7
7
0
% N
% Pro:
7
7
0
0
7
7
0
0
0
7
7
7
13
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
13
% Q
% Arg:
0
0
0
0
0
13
0
7
0
0
7
0
38
7
7
% R
% Ser:
44
0
0
44
7
44
44
0
7
7
7
7
7
38
0
% S
% Thr:
0
0
7
0
19
0
13
0
7
7
0
7
0
0
7
% T
% Val:
0
7
0
0
0
7
0
0
0
0
7
7
0
0
0
% V
% Trp:
0
7
7
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
25
0
0
0
25
7
7
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _